ANP 1105 Lecture Notes - Lecture 2: Membrane Transport, Lipid Bilayer, Extracellular Fluid

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Joanne Savory

Document Summary

Membrane: bag that contains life represents a barrier that includes the internal components and excludes the outer components. Also allows and disallows certain things in and out of the cell- taking a component form the external environment and selectively allowing things in. Extracellular fluid (fluid outside membrane) usually like salt water. Fluid mosaic- composed of a phospholipid bilayer (one end is hydrophobic and the other is hydrophilic) Peripheral proteins: attached to the integral proteins (usually internal side of pm) and be enzymes, involved in attachment functions, shape changes. Cytoskeleton: anchors to pm, can also interact with receptors. Glycocalyx: ensemble of carbs attaches to lipids and proteins on extracellular face, sugr coating pm. Glycocalyx changes when cell becomes cancerous can even change repeatedly to avoid recognition immune system. Cholesterol: overall, reduces general membrane fluidity and stabalized its structure too much cholesterol causes membranes to lose flexibility. Proteins have pores through it (channel) that allows certain aliments to pass through the cm.