ANP 1105 Lecture Notes - Lecture 5: Gamma Globulin, Buffy Coat, Spectrin

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Blood components and characteristics formed elements are short lived/disposable; replaced by bone marrow. 8% body weight (5-6 l males, 4-5 l females) Oxygen and nutrients: lungs to tissues, absorb nutrients in gut. Metabolic wastes: carries wastes to places where they can be broken down/excreted. Ph in body tissues: plasma proteins, bicarbonate reserve, buffers. Buffers are substances that can donate protons or accept protons. Co2 + h2o = h2co3 = h+ + hco3- Blood constantly adjusted to keep its composition, ph in normal range. Hematocrit: ~45% of whole blood, most dense. Buffy coat: leukocytes and platelets, less than 1% Plasma: 55% of whole blood, lots of proteins but mostly water, produced in liver. Other proteins maintain pm and regulate cell shape. Transports 20% of co2 back to lungs. Small size and biconcave shape=large surface area to volume ratio. More than 97% of non water composition is hemoglobin.

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