ANP 1105 Lecture Notes - Lecture 2: Lipid Bilayer, Fluid Mosaic Model, Signal Transduction

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Balwant Tuana

Document Summary

Fluid mosaic model of the cell membrane contains a lipid bilayer(phospholipids), a hydrophilic and hydrophobic properties, and integral membrane proteins that span the plasma membrane. The hydrophilic and hydrophobic regions contain channels, transporters, carriers, receptors, and enzyme. ***the proteins are critical in how information is transported across the bilayer. Integral membrane proteins transmit information across the bilayer. Peripheral proteins are attached to integral proteins; may be enzymes, linkers/ adaptors regulate signals/shape changes, etc . Cytoskeleton provides strength to the plasma membrane, interacts with receptors/ channels. Glycocalyx is the carbohydrate moieties proteins and phospholipids on the extracellular surface; the sugar coating on the plasma membrane. If not there, the protein could be defected. *** glycoclayx changes when cell becomes canorous-can even change repeatedly to avoid recognition by immune system. Attachment to ecm(extra-cellular matrix[various types of proteins and organizing cell, providing support, etc ]) Cell fusion mediated by integral membrane proteins of pm in adjacent cells to form impermeable junctions.