HLSC 2461U Lecture Notes - Constrictive Pericarditis, Cardiogenic Shock, Diastole
Document Summary
There are two coronary artieres ( r & l ), both start in the ascending aorta. L coronary artery is most important because it provides the blood supply to most of the l ventricle including the free wall of the l ventricle as well as the septum. When obstruction happens in cad (atherosclerosis in any of these branches) L anterior descending artery obstruction: affect the septum or part of l ventricular wall. L circumflex artery: affect only the free wall of the l ventricle. When ischemia happens, subendocardium is affected first. * main l coronary artery: affect blood supply to all branches. In the bloodstream: ldl, have receptors in the subendothelial of blood vessels, high % of cholesterol. Fibrous plaque without symptoms, stable & fixed. Partial obstruction of the flow, shows up whenever there"s ischemia in the heart. First lose the ability to electrically function well (shows up on ecg) ** damage always happens in the subendothelium first.
