BIOL 1010U Lecture Notes - Lecture 12: Semiconservative Replication, Deoxyribose, Exergonic Reaction
Document Summary
Textbook reference: chapter 12 in biology how life works (2nd ed. ) O s phase of cell cycle: virtually the same process in all organisms: O each antiparallel is complementary to the other. O the cell will replace both complementary strands of dna, each forming a template for replication. In largest human chromosome replication would take 2 months! In reality only takes a few hours: why, b/c start at multiple points of origin + bidirectional. Origin of replication specific sequence of nucleotides. Replication bubble at the origin, the dna strands separate to form this. Bidirectional replication replication proceeds in both directions until the entire molecule is copied. Leading strand at each replication fork, the new strand with free 3" end. Lagging strand new strand with 5" end replication bubble grows as replication continues: when two replication bubbles meet, they fuse to make larger bubble.
