BIOL 1010U Lecture Notes - Lecture 13: Transmembrane Protein, Thyroid, Autocrine Signalling
Document Summary
Autocrine: signals sent in the same or similar cell. Endocrine: are signals from distant cells that originate at endocrine cells (slow response) Paracrine: signals from cells that are nearby. In cell communication, it must have receptor proteins is a requirement of the responding cell. Paracrine signals move by diffusion through the extracellular matrix. Endocrine signals are located in endocrine glands like the hypothalamus, pituitary gland and thyroid gland. They produce a slower response but have lasting effects. Autocrine signals are produced in the same cell as the target cell (in other words, everything happens in the same cell) Growth factors such as platelet derived growth factor function in paracrine signaling. Notch and delta are both transmembrane proteins involve in cell communication in the developing nervous system of vertebrae animals. ^notch is a receptor and delta is a signaling molecule. Notch is a transmembrane protein tat goes straight through the cell membrane.
