PHRM 251 Lecture Notes - Lecture 1: Antimicrobial Resistance, Antibiotic Sensitivity, Medical Microbiology
Document Summary
Definition: the practice of minimizing the emergence of antimicrobial resistance by using antibiotics only when necessary and, if needed, by selecting the appropriate antibiotic at the right dose , frequency and duration to optimize outcomes while minimizing adverse effects. Formal antimicrobial stewardship services exist at many hospitals. Stewardship is everyone"s job (all pharmacists expected to participate) Recommending antimicrobials with the narrowest spectrum of activity possible (based on organisms most likely to cause the infection or c&s data) Stopping antimicrobials when they are either not indicated or when an adequate course of therapy has been completed. Stepping down from iv to po at the earliest feasible opportunity. Definition : a periodic summary of antimicrobial susceptibilities of local bacterial isolates submitted to the hospital"s clinical microbiology laboratory. Provide guidance on narrowing antibiotic spectrum based on organism isolated. Optimize opioid prescribing without compromising pain management. Develop protocols and educational materials to improve opioid prescribing. Assist with management of complex patients with pain.
