PHRM 111 Lecture Notes - Lecture 15: Meibomian Gland, Blepharitis, Warm Compress
Document Summary
Normal skin flora but problematic in excess or immune response. Dry, hard scale and crusting around eyelashes ( collarettes ) Tiny ulcerations around eyelashes: w/ chronic inflammation or severe exacerbations. Topical antibiotics provide symptomatic relief and eradicate bacteria. Acute therapy : applied on eyelid margin qhs (or up to qid) x 1-2 weeks. If effective: some practitioners extend to qhs for total 4-8 weeks (evidence?) Some patients prescribed short-term corticosteroids or corticosteroid/antibacterial combo (evidence?) Less erythema and inflammation of anterior lid margins (compared to staph) Most patients also have seborrheic dermatitis on face ( eyebrows ) and scalp. Treatment: eyelid margin care, management of concurrent seborrheic dermatitis. Thickened, waxy, white-yellow secretions; oily globules or foamy tear film. Doxycycline 20 mg po bid compared to placebo for symptom improvement. Cool , moist compresses x 5-10 minutes several times daily. Blockage and infection of glands of zeis or moll. Smaller pustule; points outward (can be seen externally)
