PHAR 471 Lecture Notes - Lecture 5: Afferent Arterioles, Angiotensin-Converting Enzyme, Efferent Arteriole
10 Dec 2016
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Document Summary
Renal structure and function: review the anatomy and physiology of the kidney, describe the tubular transport systems that permit sodium reabsorption, explain the kidney"s role in maintaining blood pressure. Rid the body of waste materials filters the blood and removes metabolic waste for excretion, then reabsorbs essentials back into the blood. Receives 20% of co from the renal arteries from the abdominal aorta. Anatomy nephron 2 major components: glomerulus (glomerular capillaries surrounded by (cid:271)o(cid:449)(cid:373)a(cid:374)"s (cid:272)apsule) = site of filtration, long tubule (proximal, loop of henle, distal and collecting duct) = site for reabsorption and secretion. Size of the ecf is largely deter(cid:373)i(cid:374)ed (cid:271)y the (cid:271)ody"s total na content because: Blood plasma: sodium is the predominant ion of the ecf influences the osmotic distribution of water, movements of na between ecf and icf are controlled by transport mechanisms diuretics almost always inhibit tubular reabsorption of na+
