PHAR 460 Lecture Notes - Lecture 20: Autism Spectrum, Risperidone, Headache

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Document Summary

Overview of nhp use in camh (child and adolescent mental health) 19. 5% in adhd; 82% in asd (autism spectrum disorder) Cam appeals to persons who are dissatisfied with the traditional healthcare system. They believe that cams provide a less invasive, more emotionally comforting approach. Cgi-s = severity of illness scale: 1=normal/not at all ill; 7=very severely ill. Cgi-i = improvement scale: 1=very much improved; 7=very much worse. Cdrs-r = children depression rating scaled revised like the hamd, but for children. Cgas = children(cid:859)s global assessment scale measure global functioning. Effect size (es) 0. 2 = small effect size. = when everyone knows what treatment they are getting. Tend to overestimate response compared to rcts. Superior to placebo for mild-moderate depression in adult trials (es = 0. 49) Not different from antidepressants (mostly tcas) in mild-moderate depression in adults. Monotherapy sjw 150-300 mg tid x 8 weeks; responders = cdrs-r<28 and cgi-s<2.

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