PHAR 460 Lecture Notes - Lecture 12: Mania, Rivastigmine, Lutein

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Cns nhps: with respect to the cns, explain why nhps might be used in: Infants: development of the brain including vision: adolescents: delayed sleep phase disorder, healthy adults: cognition, insomnia, jet lag, elderly: age-related macular degeneration, cognition. Display knowledge of the safety, possible mechanism and efficacy of the products discussed: panax ginseng, lutein, dha, melatonin, valerian, ginkgo biloba: choose products you would stock in your pharmacy. Brain development how long it takes for the brain to fully mature = 25 y/o. There are high concentrations of dha in membranes in the cns and the retina. Correlation between increased dha accumulation in the last trimester and the first 18 months after birth and rapid growth of the human brain. Theory is that dha is crucial for brain development. Health canada: no recommended intake; max 3g/day of epa+dha. Fao/who: recommend >300 mg/day of epa+dha with a minimum of 200 mg/day dha.

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