PHAR 460 Lecture Notes - Lecture 9: Horsepower, Mania, Drug Interaction
Document Summary
1. demonstrate knowledge of the safety and efficacy of 10 nhps commonly promoted for osteoarthritis. 2. counsel patients using these substances on safety issues. chronic joint pain; elderly; reduced movement; joint enlargement; progressive something (trauma, overuse, other) inflammation, enzymes destroy cartilage, bone damage, tendor, ligament, muscle damage. Relieve join pain, maintain join function, reduce progressive joint damage, avoid surgery. Improvement in pain or in function of at least 50% with a decrease of 22 m on the vas for pain or function. Improvement in both pain and function of at least 20% with a decrease of 10 mm on the vas. Potential weaknesses in studies of oa: allow use of other pain medication, no placebo group, statistical significance versus clinical significance. General overview of each possible nhp for oa. An amino sugar used to make cartilage and oher structures. A component of cartilage synthesized in the body. Synthetic, but occurs naturally in green plants, fruits, vegetables, grains and in the human body.