PHAR 454 Lecture Notes - Lecture 11: Hydronephrosis, Diarrhea, Lionsgate
Document Summary
Pediatric uti: describe the pathophysiology of uti in children, describe the clinical presentation of uti. By 7 years: girls = 8%; boys = 2% Age: <1 yr = 75%; >1 yr = 30-40% Probably because children <1 y/o who get a uti usually have some sort of urinary tract abnormality, whereas older kids who get a uti is usually related to toilet training = less risk of recurrence. Problem: many studies do not show benefits in preventing these complications. Ascending: bacteria colonizes in the urethra, enters the bladder and potentially to the kidneys. This is the most common cause in kids. Hematogenous (rare outside neonatal period): bacteria gets into the blood somehow (lungs, broken skin, etc. ) and infects the urinary tract. Sex: in infant period male = risk factor; outside of infant period female = risk factor. Anatomic abnormality vesicoureteral reflux (vur - urine refluxes back into the kidney from the bladder), urethral strictures, posterior urethral valves.