PHAR 201 Lecture Notes - Lecture 15: Anesthetic, Neuron, Malignant Hyperthermia
16 Dec 2015
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Give a brief overview of the history of anesthesia. Associated with actual or potential tissue damage. Or described in terms of such damage. Use drugs to induce insensibility to sensation (particularly pain) Local and general: anesthetic binds to and inhibits the function of sodium channels on nerve cell membranes (basically an antagonist, nerve transmission to pain centers in the cns blocked. Have been used for 150+ years, but mechanism of action. Generalised cns depression with no effect on cardiac or very unknown respiratory functions. Amnesia always seen (otherwise, condition known as. Anti-nauseants, opioids, sedatives, induction drugs, muscle relaxants (for intubation), reversal drugs, cv drugs (stabilizing bp & hr), antibiotics, local anesthetics. Describe the mechanisms, instrumentation, and side effects of vapour. What is the route of administration/eli mination for. Delivered through the airway to the lungs, and then absorbed into the bloodstream through the alveoli.
