PCTH 201 Lecture Notes - Lecture 12: Amide, Ondansetron, Coronary Artery Disease

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Objectives: understand the risk factors and management of nausea and vomiting after surgery, understand the basic mechanism of action and complications analgesic medications used after surgery. When surveyed, patients consistently rank pain and postoperative nausea and vomiting (ponv) as the two outcomes that they would most like to avoid. Ponv: any nausea, vomiting or retching ( ) that occurs in the first 24 hours after surgery, common after surgery: occurs between 10 and 80% of patients, risk: greatly depends on the number of risk factors, major risk factors: Note: the risk of ponv increases with increasing number of factors. Strategies used to reduce ponv include: avoid volatile anesthesia, use neuraxial (spinal or epidural anesthesia) or regional anesthesia instead of general anesthesia, minimize the use of opioid medications, administer ponv prophylaxis medications. Pain management options in the postoperative setting (increasing analgesic requirements):

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