MICB 306 Lecture Notes - Lecture 11: Dna Replication, Mutation Rate, Motility
Document Summary
Cancer is a disease caused by uncontrolled cell division that leads to a growth of cells that invade nearby tissues and spread to other areas of the body the development of a tumor is a multi-step process: Increase their rate of proliferation, become immortal, capable of infinite replication: change their morphology, adhesive properties, capacity to be motile . The development of cancer is a by product of infection: growth-promoting properties of the virus have oncogenic potential. They directly or indirectly contribute to the development of a cancerous cell: for example, : directly through viral proteins directly impacting cancer. When these viruses overcome the ability of the host to maintain homeostasis, they trigger cellular changes ultimately leading to cancer. Signaling mimicry: viruses encode proteins that are able to subvert, in a dominant manner, host-signaling mechanisms that regulate cell growth and survival.
