BIOL 125 Lecture Notes - Lecture 16: N-Formylmethionine, Aminoacyl-Trna, Helicase
Document Summary
Folding determines a protein"s tertiary structure and therefore its function: they might get or lose a phosphate group (switching the protein from an inactive state to an active state or vice versa). The active site of the ribosome is entirely ribosomal rna. Thus, ribosomal rna catalyzes peptide bond formation and the ribosome is a ribozyme. Termination occurs when the a site encounters a stop codon. A release factor enters the site it resemble trnas but does not carry an amino acid. It breaks the bond linking the trna in the p site with the polypeptide chain. Initiation: the initiation phase of translation begins at the. Aug start codon: the interaction between the small subunit and the mrna is mediated by initiation factors. In prokaryotes: the mrna binds first to a small ribosomal subunit, the initiator f-met (aminoacyl trna bearing n- formylmethionine ) binds to the start codon, the large ribosomal subunit binds, completing the complex.
