PSYCH261 Lecture Notes - Lecture 7: Neural Darwinism, Synaptogenesis, Frontal Lobe
28 Nov 2015
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Proliferation of neurons: migration (neurons going to certain locations, differentiation (neuron gets its particular axons and dendrites that give it a particular shape, myelination, synaptogenesis. Sperry (much like neurons trying to find certain places, axons themselves follow chemical gradients) Topography, dorsoventral (they try to find the place where there is high in. Transsected the optic nerve and rotated the eye (anterior to posterior, posterior to anterior) The axon finds its original (old) place even when the eye was rotated, even when they were in the opposite side (rewires to where it should have been in the first place) The axons know where to go even when you rotate the eye. Initially neurons don"t have myelin in them (no nodes of ranvier) Full myelination doesn"t occur until 18-21 years old. Spinal cord, hindbrain, midbrain, and forebrain (myelination occurs in order) Occurs throughout entire lifespan as you learn. Axon attaches to motor muscles make contact, form terminal button formation of clear synapse.
