KIN242 Lecture Notes - Lecture 5: Intracranial Aneurysm, Physical Medicine And Rehabilitation, Dlg4
13 Mar 2017
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Document Summary
Stroke treatment: goals, acute, stabilize, minimize damage (cell death, may include neurosurgery, medications, sub-acute, facilitate neurologic and functional recovery, prevent additional injury / complications, chronic, fewer options available, continuing rehab is valuable. Acute treatment: thrombolytic agent (clot-busting drug, dissolves blood clots, only drug approved by the health canada for the acute treatment of ischemic stroke. Acute treatment outcomes: without tpa, survivors, 5% minor symptoms, 50% moderate symptoms, 45% severe symptoms, with tpa, surivors, 20% minor symptoms, 40% moderate symptoms, 40% severe symptoms, but, a small number suffer a brain haemorrhage. Intra-arterial tpa (iat: downside: you need a lot more skill therefore not used as often. Clot retrieval: chance of puncturing vessel is higher thus not used as often. Na-1: psd-95 inhibitor: reduced infarct volume in stroke and humans, humans: stroke after surgery (intracranial aneurysm repair, after this repair = high chance of stroke, first positive trial in stroke since tpa, rct will have administration in ambulance.
