BIOL479 Lecture Notes - Lecture 5: Coefficient Of Relationship, Zygosity, Assortative Mating
3 Feb 2016
School
Department
Course
Professor
Document Summary
Assortative mating: any type of mating where mate choice is based on phenotype. Maximize diversity, fitness significant heterozygote excesses at mhc loci. Assortative mating refers to phenotype based matings that have a higher or lower frequency than expected by chance in a randomly mating population. Inbreeding: increase homozygo at all loci increase autozygosity results in hw disequilibrium with heterozygote deficits. F=0, no inbreeding and genotype freq. will be the same as. Inbreeding coefficient (f) = (h_exp h_obs) / h_exp smaller pop. > increase inbreeding chance expected under random mating. F=1, completely inbred population with no heterozygotes. Must be homozygous identical by descent: allozygous (possess two alleles at a locus that are not. Feq (equilibrium inbreeding coefficient) = s/ (2-s) S= proportion of progeny produced by self-fertilization. Recall: only recombination in double heterozygotes break down gametic disequilibrium at a rate of r. Retard the rate which gametic disequilibrium breaks down as it decreases the number of double heterozygotes.
