BIOL355 Lecture Notes - Lecture 30: Heart Failure, Anti-Inflammatory, Coronary Circulation

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Pressure builds up where blood can"t get through. Weakend segment of a blood vessel upstream of the plaque or embolus bulges out and may rupture aneurysm. May lead to stroke, severe headaches, internal bleeding, unconsciousness, death. Usually at areas where there is bifurcation (branching of artery) Nih labeled ldl-cholesterol level below 100 mg/dl. Increase glucose, glycation, inflammation oxidation of ldl, inflammation causes vasoconstriction, hr causes platelet stickiness -> risk of thrombus serum lipid level monoxide (displace o2 from hemoglobin) Antiotensin ii: hormone responsible for high bp also appears to incite inflammation rxn. Infections reduces inflammation by carrying antioxidants in blood to break down. As aging, reduce cholesterol/saturated fats in your diet cholesterol should be 300mg/day. High alcohol consumption -> ldl coffee -> ldl. Males have higher risk of cv disease. Bp smoking + birth control heart attack risk 18-fold. Add toxins to blood -> plaque formation. Exercise raises hdl"s in blood lowers ldl. As well as workload for the heart.

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