BIOL355 Lecture Notes - Lecture 27: Valvular Heart Disease, Coronary Artery Disease, Heart Failure
27 Aug 2019
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If in left ventricle then results in backup of blood via pulmonary vein into lungs: heart attack, heart valve disease, high bp, stress, obesity, anemia, lung disease, infections. Increased glucose, increased glycation, more inflammation: smoking. Causes vasoconstriction and increased heart rate ( workload heart) Causes platelet stickiness increasing risk of thrombus) Increases serum lipid levels and increases carbon monoxide which displaces. Infections: some bacteria such as chlamydia pneumonia (respiratory infections) can induce or aggravate atherosclerosis, found c. pneumonia associated with plaques, diet. In the u. s. it"s about 450-600 mg/day: gender. Promising drug therapy: vasodilators nitroglycerin reduce peripheral resistance and therefore workload for the heart act as coronary vasodilators, beta-blockers used to treat hypertension, dysrhythmias as well as angina. Balloon angioplasty: a smaller guidewire is advanced across the blocked section of the coronary artery and a balloon - tipped catheter is positioned so the balloon part of the catheter is beside the blockage.
