BIOL302 Lecture Notes - Lecture 7: Intramembranous Ossification, Haversian Canal, Dense Irregular Connective Tissue

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Bone as a tissue is properly classified as a connective tissue. However, it is difficult to separate bone as a tissue from bone as an organ. Therefore we will look at bone as both a tissue and organ system. Bone as a tissue is the structural component that makes up much of the supportive elements of our skeleton. Bone as an organ system serves as an attachment for muscles and ligaments, protects the vital organs of the thorax and the central nervous system, acts as the major source of blood cells, and stores calcium and phosphorus. Like all connective tissues, bone is composed of cells, fibers, and ground substance. What makes bone stand out from most connective tissues is that the ground substance of bone is calcified to provide a rigid structure. The matrix of bone consists of organic and inorganic substances. Proteoglycans, chondroitin sulfate and collagenous fibers form the organic matrix.

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