BIOL240 Lecture Notes - Lecture 7: Peptidoglycan, Periplasm, Lysozyme
15 Mar 2019
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Cytoplasmic membrane protein: does not provide membrane rigidity. Cell wall: give cell shape mreb works with cell wall. Cell wall builds itself around it again acting like a scaffold: protects from lysis and mechanical forces, crosslinked strands of peptidoglycan subunits. Cell wall -> periplasm -> cell membrane. Mreb is the helix which helps give strength to the cell wall. Cell wall helps the cell survive through harsh conditions. Protects from osmotic lysis (keeps everything including mem. inside) Cell wall is a matrix of peptidoglycan (peptido amino acids and glycan which is sugar) which are crosslinked for higher strength. Peptidoglycan made of n-acetylmuramic acid (nam) and n-acetylglucosamine (glucose amine which is wat nag is made of) (nag) and also has small peptide chains. Nam is the only sugar that can link with the oligopeptides (4 aa) In gram -ve bacteria like e. coli, the linking between chains happen between 2 adjacent peptide chains.
