BIOL130 Lecture Notes - Lecture 5: Sigma Factor, Tata-Binding Protein, Phenylalanine
30 Nov 2015
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Genotype effect/activity of protein phenotype (physically observable) 3d four different bases to choose from, and different types of sugar used to form them influences stability properties bw long lived information depository and one that mediates movement of information. Different types of rna found in the cell transcription from dna template. Rna polymerase enzyme that catalyses snythesis of phosphodiester bonds is rna polymerase. 10 box 10 bases upstream from start site. Termination holoenzyme direct downstream dna toward its active site: rnapol reaches a transcription termination signal in dna template, rna polymerase separates from rna transcript codes for rna that folds back on itself (short double helix), forming hairpin structure. *****not stop codon, that"s translation***** hairpin disrupts transcription complex. 5" cap, poly (a) tail eukaryotic genes can be spread out, with gaps of up to 100,000 bps of untranscribed. Dna between them allows for complex regulation of gene transcription by regulatory sequences scattered through genome.
