BIOL130 Lecture Notes - Paraxial Mesoderm, Olfactory Bulb, Fasciculation
Document Summary
Sensory receptor cells sensory cilia related to motile cilia, but central tubules are missing. Light: rod photoreceptor uses rhodopsin and g-protein pathway for a. p. and nt release. Sound: ciliary movement directly opens/closes membrane channels hair cells. 1,000 different odorants can be detected rod rhodopsin hair cell. Genetic defects of cilia more than one cell affected (usher"s synd. ) Eye forebrain epithelium grows out becomes optic vesicle vesicle becomes retina lens forms from ectoderm optic vesicle. Ear/nose from thickened surface ectodermal placodes ear: otic placode otic vesicle hair cells nose: olfactory placode. **primordial tissues are source of neurons and inductive signals for rest of organ** ectodermal placodes. Bmp 4,7 after contact is made between optic vesicle and lens placode: Lens placode pinches off to form lens and surface corneal epithelium. Optic vesicle away from lens becomes retinal pigment epi. (for photoreceptors) lens, surface corneal epithelium retinal pigment epithelium. Edge of optic cup forms the iris.