BIOL130 Lecture 2: Biological Membranes Week 6

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All cells have a plasma membrane that encloses the entire cell. Eukaryotic: membrane bound organelles: nuclear envelope, double membranes of mitochondria and chloroplasts, er, golgi apparatus, lysosomes and vacuoles, transport vesicles etc. Provide a selectively permeable barrier: prevent unrestricted exchange of molecules. Transport solutes: exchange of molecules across the membrane. Respond to external signals by signal transduction: signal travelling from a distance or from nearby cells. Compartmentalization (eukaryotes: create separate environment for different activities. All membrane lipids are amphipathic, hydrophobic and hydrophilic. Fatty acid chain/tail is hydrophobic while the rest is hydrophilic or polar. Glycerol, phosphate, and polar head group are all polar and hydrophilic. Their contents can flow freely past each other, they are not static. Tra(cid:374)sitio(cid:374) te(cid:373)perature: te(cid:373)perature at (cid:449)hi(cid:272)h a (cid:373)e(cid:373)(cid:271)ra(cid:374)e (cid:858)gels(cid:859) or solidifies. Above temperature the membrane is fluid, below it is compact and not as fluid. Temperature can determine fluidity: high temperatures, membrane more fluid, low temperature, membrane less fluid.

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