BIOL130 Lecture Notes - Lecture 1: Peptide, Stop Codon, Golgi Cell
Document Summary
You are an amino acid in the lumen of the small intestine from a recently digested protein meal, faced with a wall of intestinal epithelial cells. You have always been intrigued by the idea that cells had their own digestive systems. Your ambition is to be incorporated into a lysosomal enzyme within one of those intestinal epithelial cells. You will be asked to describe your adventures during one of three phases of that journey: beginning from the challenge of entering the cell, until you have been loaded onto an appropriate trna. The small intestine uses different enzymes and processes to digest proteins, lipids, and carbohydrates. The lumen refers to the inside space of the tubular small intestine. The first challenge that the amino acid faces is actually entering the intestinal epithelial cell, which are specialized for absorption. The routes that lead inward from the cell surface to lysosomes start with the process of endocytosis, which takes up macromolecules.