NUTR 120 Lecture Notes - Lecture 13: Sickle-Cell Disease, Nutrasweet, Phenylalanine
Document Summary
The condition pku: phenylketonuria is when you are unable to breakdown. All have hydrogen, an amino group, and a carboxyl group. The amino acid phenylalanine is a component of aspartame and nutrasweet. Secondary structure: shapes within final protein (alpha-helices or beta-sheets) Tertiary structure: final three dimensional structure of protein. The amino acid sequence of a protein determines its final 3d shape. A protein"s shape is critical to its function: Denaturing a protein is changing its shape and function by applying heat or chemistry. Altering amino acid sequence can change protein function dramatically: Has four identical protein units (quaternary structure) Heme containing four iron are in the middle of the structure. One amino acid change alters the red blood cells. Even one amino acid change can result in a change of shape and therefore of function. Hemoglobin protein (300 amino acids: cereal products, dairy products, meats. Normal turnover (breakdown, repair + replacement of all body tissues/organs.
