PSYC 2490 Lecture Notes - Lecture 3: Nuclear Pore, Competitive Inhibition, Galactose
5 Mar 2018
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Document Summary
Membrane proteins have four major functions: membrane spanning transport protein: protein mediated transport across a membrane. Membrane enzymes: catalyze chemical reactions taking place on the cells external surface or internal: transporting signals from the external environment to the cytoplasm. Organization type 1: abc superfamily: atp-binding cassette, use atp"s energy to transport small molecules or ions across the membrane, slc superfamily: solute carrier, facilitated diffusion and some active transporters. Structure: membrane spanning protein subunits, form a pore cluster of cylinders. Naming: named according to what they allow to pass, water channels: made from aquaporins, allow water to pass. Ion channels: specific for one or similar ions, non-specific monovalent channels: allow similar single charged ions to pass. Uniport carriers: move only one kind of molecule. Cotransporter: moves more than one kind of molecule at a time, symport carriers: moves more than one kind of molecule in the same direction, antiport carriers: move more than one kind of molecule in opposite directions.
