MBIO 2020 Lecture Notes - Lecture 4: Ribosomal Rna, Messenger Rna, Ratp Group
25 Nov 2017
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Figure 4. 20. the sigma factor recognizes the promoter region and initiation site. Transcription begins, sigma is released and rna chain grows. Synthesis occurs in the 5" to 3" direction. Transcription on the dna can happen multiple times at once generating many many. Bacterial structural gene strand (same as before: 1. Promoter: recognition and binding site for rna polymerase feature -35 and -10 boxes: 2. Leader sequence: transcribed into mrna but not translated transcription begins at position +1 which is where the leader sequence starts: 3. Coding region: transcribed and translated into polypeptide (i. e protein: continuous (not interrupted by introns, 4. Trailer: transcribed into mrna but not translated: prepares rna polymerase to release the template strand. Rna polymerase large multimeric enzyme (a. k. a. core enzyme) catalytic activity: 2 alpha subunits, 1 beta, 1 beta prime, and one gamma (w) target site of rifamycin class of antibiotics, 2.
