MBIO 1010 Lecture Notes - Lecture 11: Glycoprotein, Non-Cellular Life, Lytic Cycle
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Eukaryotes have: lower surface area to volume ratio, need more sophisticated transport mechanisms, grow slower can"t absorb as much nutrients as prokaryotes can for their, the surface/volume = 1. 5 in eukaryotics. 2. 20 the nucleus and cell division: eukaryote (true nucleus, genetic material is housed in a nucleus, generally larger than prokaryotes, complex internal structure, membrane bound organelles. Intracytoplasmic membranes used for transport: cytoskeleton, divide by mitosis and meiosis. Key differences between prokaryotic cells and eukaryotic cells: * some eukaryotes have some 70s inclusions inside them, this can be targeted by drugs that target the infectious. 70s ribosome structure, these do not target our cells but only the ones that are unwanted. The nucleus: holds the genetic information, multiple linear dsdna chromosomes. Mitochondria: site of respiration and oxidative phosphorylation, surrounded by 2 membranes, dna and ribosomes (70s) Rickettsia (a proteobacteria: obligate intracellular pathogens (ex: rocky-mountain spotted fever)