BIOL 2420 Lecture Notes - Lecture 32: Adipose Tissue, Fatty Acid Metabolism, Acetyl-Coa
9 Mar 2018
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Document Summary
Unit 4: digestive system physiology (g: post-absorptive sate: Lipolysis: the catabolism of triglycerides glycerol + fas, glycerol is used to produce glucose in the liver. Glucose from protein sources: proteins catabolize aas which enter the blood, the liver takes the alpha-ketoacids and produces glucose. These processes can provide 25-50% of the daily glucose requirement: glucose sparing. Most organs/ tissues reduce glucose catabolism in the post-absorptive state. Less important tissues use lipids during post-absorption. The free fatty acids can enter all tissues because they"re hydrophobic and small (except for the nervous system it only gets glucose) It"s influenced by the plasma glucose concentration: has an effect on muscle, liver and adipose tissue (only places that store glycogen) Adipose tissue converts glucose to fats: effects of insulin on tissues: More glut transporters are trafficked to the surface of the plasma membrane the cell becomes more permeable to glucose (glucose enters cell down its concentration gradient)
