BIOL 1030 Lecture Notes - Lecture 15: Myelin, Saltatory Conduction, Schwann Cell

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BIOL 1030 Full Course Notes
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This mechanism for action potential propagation is called saltatory conduction. In the brain, the white matter is axons covered by myelin sheath, the grey matter is unmyelinated. Information is transmitted to cells at synaptic terminals, cells are physically separated: electrical signal must be converted to a chemical signal to communicate between cells, chemical signalling molecules are known as neurotransmitters. : di use out of the synaptic terminals into the receiving neuron. Synapse presynaptic events: presynaptic terminal contains voltage-gated ca++ channels, when signal reaches terminal, ca++ channels open, allows calcium to enter from the outside of the cell. Increases the membrane potential, known as excitatory postsynaptic potential (epsp: getting closer to threshold potential, requires many to reach threshold, some are inhibitory neurotransmitters, has a negative impact on target cell. Lowers membrane potential, makes it more di cult for the cell to reach threshold potential. Net effects: at a target cell, several neurotransmitters are being sent at once.

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