ZOO 3000 Lecture Notes - Lecture 1: Basal Lamina, Myosin, Neuromuscular Junction

• School: University of Guelph
• Department: Zoology
• Course: ZOO 3000
• Professor: Fred Laberge

Document Summary

100um: nuclei are ovoid and peripheral, cytoplasm is acidophilic and striated, each dot = myofibril (picture 1 on far left) Structure of skeletal striated muscle: cells are bound by 3 layers of ct, endomysium immediately around muscle fiber, perimysium binds fascicles (i. e. groups of muscle fibers, epimysium surrounds the entire muscle. Skeletal striated muscle fiber types: skeletal muscles have 3 fiber types: Contraction at cellular level: sarcomeres shorten during muscle contraction because of the thin filaments actively sliding along the thick filaments, structural accessory proteins, such as titin, maintain alignment and spacing in sarcomere. Regulation of muscle contraction: myofibrils are surrounded by the transverse tubular system and the. Sarcoplasmic reticulum: t tubules couple extracellular events (nerve stimulation) with intracellular responses (ca2+ release, sarcoplasmic reticulum sequesters ca2+ at rest but when the muscle is stimulated via nerve impulses, calcium is released from the sr.