PSYC 3030 Lecture Notes - Lecture 2: Growth Factor, Cyclic Adenosine Monophosphate, Chemical Synapse

• School: University of Guelph
• Department: Psychology
• Course: PSYC 3030
• Professor: Rob Foster

Document Summary

Anterograde transport (communication from the cell body to the axon in a neuron: cytoskeletal and soluble proteins, vesicles containing: proteins for growth, mitochondria, proteins/enzymes needed for neurotransmitter synthesis & secretion. Retrograde transport: vesicle membrane material and excess or degenerated axon proteins, nerve growth factor (ngf) are neurotropic factors, they"re very specific. Activity at an axoaxonic synapse may cause presynaptic inhibition or presynaptic facilitation. Amino acids a few, play other metabolic roles besides their role as neurotransmitters. Acetylcholine typically they"re small and soluble, but are ionized at physiological ph, thus reducing their tendency to diffuse through the blood-brain barrier. Synthesized from dietary precursors, and transformed in active compounds by a series of biochemical reactions. Neuropeptides long or short chains (3-40) of amino acids derived from proteins precursors synthesized in the cell body. Now we know that many neurons make and release two, three and occasionally even more, different transmitters.