PSYC 3030 Lecture Notes - Lecture 2: Beta Blocker, Peritoneal Cavity, Atropine
Document Summary
Principles of pharmacology: determinants of drug action, pharmacokinetics. Morphine (drug a) on neural site 1, produce analgesia (drug effect x) Neural site 1 effects neural site 2, causing pupil contraction (drug effect y) Drug a affects neural site 3, which causes respiratory depression (drug effect z) Drug drug action (molecular changes) drug effect (physiology/psychology: the same drug can have multiple actions and effects. Therapeutic effects vs. side effects: site of the drug action is not always the site of the drug effect. Do not cross the blood brain barrier, instead work in the periphery. Blocks beta agenergic receptors: similar drug effects can be initiated by different drugs/actions. Atropine (drug b) effects neural sites 1 and 2, causing drug effects x and y. Chemical structure of a drug is highly related to affinity for targets/receptors. Where the drug acts (on target sites/receptors): multiple receptors and locations. Dose: related to the speed of action and ultimate effects.