POPM 4230 Lecture Notes - Lecture 18: Bovine Virus Diarrhea, Human Respiratory Syncytial Virus, Coccidiosis

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Upper respiratory to bronchopneumonia (front portion of lungs affected) Dead space: area in the lung that is not being well ventilated, pathogens can sit in there, oxygen not flowing well at that area. Hair on nostrils, squamous epithelial cells in the nose, trachea has cilia to remove particle passing by, mucus in trachea bind particles. Immune cells in the lungs, cells overreact to the pathogens going in, it causes significant changes that are irreversible (firm area in lung) Often initiated by environmental stressors and viral infections. Impacts the ability for lungs to get rid of pathogens. Increased risk of brd occurs with (which happens commonly post-weaning) Light weight or younger animals within a group (mixed with older animals) Persistent infection with bvdv (bovine viral diarrhea virus) (suppress immune system and not able to respond to the pathogens) Morbidity is high but mortality is low (mild to moderate resp diseases) Mostly affects calves that are 2-6 months old (post weaning)

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