POPM 3240 Lecture Notes - Lecture 1: Postpartum Infections, Percivall Pott, Genetic Epidemiology

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Disease, illness, and ill health are not randomly distributed in human populations: we have certain characteristics (genetic, environmental) that predispose us to, or protect us against, a variety of diseases. To identify the etiology or cause of a disease and the relevant risk factors: aim is to intervene to reduce morbidity and mortality from the disease, allows us to develop a rational basis for prevention programs. To determine the extent of disease found in the community: critical for planning health services and facilities and for training health care providers, screening for disease. To study the natural history and prognosis of disease: define the baseline natural history of a disease in quantitative terms, compare modes of intervention used (find effectiveness, clinical effectiveness of treatments. To provide the foundation for developing public policy relating to environmental problems, genetic issues, and other considerations regarding disease prevention and health promotion. Accuracy and interpretation of clinical diagnostics/tests (false positive and negatives)

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