POPM 3240 Lecture Notes - Lecture 3: Type I And Type Ii Errors, Tuberculin, Biomarker

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Tests any assessment of decision, including critical examination, observation, or evaluation: use tests to determine the health and disease outcomes, but also potential exposures, test can help us determine who is: Two main categories of tests for health and disease outcomes: screening tests. Used on apparently healthy individuals to detect subclinical disease. Provides an early indication of a pathological disease process or limited health/productivity outcome: diagnostic tests. Used on sick individuals with clinical disease to confirm, classify, inform treatment, or provide a prognosis for a particular disease. Bimodal curve type of distribution of population, two peaks present: able to separate most of the population into two groups, eg: distribution of tuberculin reactions (experience vs. no experience with tuberculin) In general, most human characteristics are not distributed bimodally. Unimodal curve a single peak distribution: choose cutoff on the basis of biologic information . U(cid:374)fortu(cid:374)atel(cid:455), for (cid:373)a(cid:374)(cid:455) hu(cid:373)a(cid:374) (cid:272)hara(cid:272)teristi(cid:272)s, (cid:449)e do(cid:374)(cid:859)t ha(cid:448)e that i(cid:374)for(cid:373)atio(cid:374) to ser(cid:448)e.

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