PATH 3610 Lecture Notes - Lecture 6: Intracellular Parasite, Animal, Mycobacterium

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Susan Bland

Document Summary

Considered on basis of structural complexity of organism; simplest to most complex: Prions < viruses < intracellular bacteria < mycoplasma < the bacteria < fungi < protozoa < metazoa < arthropods. Also considered on basis of site of multiplication: obligate intracellular organisms/parasites: require hot cells to grow & multiply, using hosts metabolic machinery for growth; tend to infect parenchymal cells. Cultures require living cell systems (i. e. tissue cell culture or embryonated eggs) Prions, viruses, rickettsia & chlamydia (intracellular bacteria: facultative intracellular organisms: can grow inside (esp. macrophages) & outside cells. Cultured either on specialized arti cial media or in cell culture. Some fungi, mycobacteria: extracellular organisms: multiply outside of cells. Can be cultured on arti cial media; *exceptions of protozoa & metazoa. Prions: simplest, i. e. agent that causes mad cow disease. Viruses: classi ed as rna or dna viruses, basis of type of nucleic acid in their genomes. Bacteria: includes intracellular bacteria (rickettsia & chlamydia), mycoplasma (simple form)