NUTR 4320 Lecture Notes - Lecture 2: Lactose Intolerance, Glycosidic Bond, Monosaccharide
4 Feb 2019
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Lactose hydrolysis in small intestine: lactase responsible for breakdown of lactose, expressed in jejunum and ileum, break glycosidic bond in lactose to release glucose and galactose, uses water. Digestion of disaccharides: locations of enzyme in microvilli brush boarder on apical side. Monosaccharide absorption *hint easy exam question: enterocytes/epithelial cells (small intestinal cells that line the brush boarder, 2 borders must be crossed to enter the bloodstream, 1. Absorption (transport: use to test self on absorption of glucose and galactose, starting in the small intestine (jejunum, 1. Active (atp) transport of na+ from enterocyte to blood: 2. [na+] inside cell = facilitated diffusion of na+ inside cell: 3. Sglt1 transporter needs both na+ and glucose to work (co-transport: na+ and glucose inside cell, *** fructose uses glut5 instead of sglt1, 4. * fructose uses glut5 instead of slgt1 on apical side (na+ independent)
