NUTR 3210 Lecture 3: ProteinLec3
4 Apr 2017
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The body is very efficient of recycling aa for protein translation (~80% reutilized, 20% degraded) Breaking down aas will generate carbon backbone and ammonium. Carbon skeleton can be either glucogenic or ketogenic to make glucose or acetyl. These can either be broken down directly for energy or contribute to the synthesis of glycogen or triglyceride. Ammonium will either go into the urea cycle or directly secreted in urine depending on the blood ph. In fed state, both glutamine and alanine are used as interorgan nitrogen carrier to carry ammonium from non-hepatic tissue (mostly muscles) to the liver. excreted as urine. Liver converts ammonium into urea with is then transported to the kidney and. The carbon skeleton is also called alpha-ketoacid. When this gets broken down, bicarbonate is released (from kreb"s cycle), and is neutralized by using hydrogen ions in the blood (producing co2, which is expired by lungs)
