NUTR 3210 Lecture Notes - Lecture 60: Sertoli Cell, Spermatid, Spermatocyte

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Sertolli cells are where sperm are produced. The cells are right against the basement membrane. The cell then moves through the semineferus tubules towards the beginning, while moving they are developing. Sertolli cells protect sperm from the immune system: the basement membrane is the blood-testis barrier, sertoli cells produce fas-ligand which binds to a fas-receptor on t-cells. So, are they single celld organisms: who knows. In the form that they are released they are not capable to fertilize an egg. They must be modified by the female reproductive tract: the female reproductive tract help to remove less than optimal sperm by phagocytosis, capacitation is the alteration of the glycoprotein service of the sperm by the female reproductive tract. This is specific to mammals: enzymes remove surface proteins, revealing underneath molecules that are needed to bind to the egg, corona radiata is the outermost layer of the egg. In vitro fertilization is used in agricultural practices.

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