MBG 1000 Lecture Notes - Lecture 2: Open Reading Frame, Aminoacyl-Trna, Stop Codon

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puceporpoise629

6 Apr 2016

School

University of Guelph

Department

Molecular Biology and Genetics

Course

MBG 1000

Professor

Georgevander Merwe

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Document Summary

Rna polymerase (the enzyme that makes rna from dna) it binds to the core promoter. Protein-coding region: speciies the amino acid sequence of the protein. Acivators and repressors are dna regulatory elements = nucleoide sequences: speciic to corresponding binding proteins. Bound by regulatory proteins that can either be: acivators: posiively impact transcripion, they acivate it, need to bind to the. Dna: repressors: inhibit transcripion, negaively impacts rna polymerase (enzyme), need to bind to the dna. There are speciic genes that need to be repressed (ex. the gene of your eye colour is repressed in your heart cells: acivators and repressors are proteins. 2: if there is no regulaion, diseases will occur. All ribosomes are synthesized in the nucleus. The cells spend of its energy making and exporing the ribosomes. Structure: consists of two parts; large and small subunits. Each subunit consists of proteins and ribosomal rna molecules: contains three sites to which trna molecules can bind.

Related Questions

1. The Pribnow Box is a

A. attenuator

B. enhancer

C. promoter

D. operator

2. Which of the following do not occur during post-transcriptional processing of RNA in eukaryotes?

A. the splicing of introns

B. addition of a poly-A at the 3' end

C. removal of introns

D. addition of a 7-methyl guanosine cap at the 5' end

3. In transcription, RNA polymerase binds at

A. a promoter

B. an operator

C. the oriC locus

D. an enhancer

4. The Central Dogma in genetics describes

A. the pattern of information flow in the cell

B. the pattern of chromosomal inheritance in populations

C. the role of mutations in disease

D. the role of promoters

5. Which of the following sequences of DNA could code for a stem-loop structure (only the template strand is shown)?

A. 3'--G-G-C-C-C-T-T-G-G-A-A-A-A-C-C-A-A-G-G-G-C-C--5'

B. 3'--G-G-C-C-C-T-T-G-G-A-A-A-A-G-G-T-T-C-C-C-G-G--5'

C. 3'--G-G-C-C-C-T-T-G-G-T-T-T-T-G-G-C-C-C-T-T-G-G--5'

D. none of the above

6. Removal of introns from RNA is by

A. primosomes

B. peptidases

C. galactosidases

D. spliceosomes

7. Which of the following represents the units for measuring the rate of sedimentation of a molecule/organelle in a sucrose gradient?

A. molecular weight

B. Svedberg units

C. map units

D. Daltons

8. During transcription, which strand is not read by the RNA polymerase?

A. coding strand

B. noncoding strand

C. template strand

D. terminator strand

9. The function of the rho protein is

A. to help terminate translation

B. to help RNA polymerase bind to the DNA

C. to help RNA polymerase find a promoter

D. to help terminate transcription

10. The unusual bases found in transfer RNAs

A. are added during transcription

B. are normal bases that have been modified after transcription

C. help the tRNAs to bind to DNA

D. ensure that the tRNA stays linear in solution

MBG 1000 Lecture Notes - Lecture 2: Open Reading Frame, Aminoacyl-Trna, Stop Codon

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