HK 3100 Lecture Notes - Lecture 15: Noxious Stimulus, Nociception, Sympathetic Nervous System

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" an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage" Aging population: a growing concern: during our working life we will be dealing with an aging population with chronic pain. Lots of variation (same stimulus but different interpretation) pain population: pain, a very complex, subjective experience, the processing and subjective experience of pain incorporate brain centers involved with emotion learning, memory and reward. "expected" pain was experimentally manipulated participants told the pain was greater or less than actual. "expectation of decreased pain profoundly reduced both the subjective experience of pain and pain-related brain activation" Characteristics of acute/chronic: acute, short duration, well-defined cause, decreases with healing. Inflammation (e. g. cuts and sprains which cause tissue disruption) Ischemia (oxygen starvation: characteristics, sharp, well localized, reproduced by touching or moving the area or tissue involved. Nociceptive pain: visceral pain: visceral pain source.

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