EQN 3060 Lecture Notes - Lecture 20: Udder, Surcingle, Vaginal Discharge

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Initiation of foaling controlled by the fetus but the mare can control (delay up to 24 hours when the environment is right for her) Increased estrogen then it decreases just before birth. Increased p4 (progesterone), then decreases just before birth. Increased prostaglandin (pgf), oxytocin and relaxin at birth. Endocrine of parturition the threshold level it signals that the foal is ready to be born increases as parturition gets close. Fetal cortisol is the true initiator of parturition when it reaches. Increased estrogen, then decreases just before birth: comes from the placenta, stimulates pgf from uterus, changes mucus, releases cervical plug, contributes a little bit to smooth muscle contractions. Increases then decreases just before birth: from placenta, probably ratio and sudden drop of p4:e helps initiate parturition. In late gestation causes pelvic ligament relaxation: allows passage of foal through the birth canal. Increases at birth: from fetus, placenta, and uterus, stimulates uterine contractions.

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