EQN 3060 Lecture Notes - Lecture 8: Granulosa Cell, Corpus Luteum, Luteolysis

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Hormones regulate activity of target cells effective at low doses. Hypothalamus (gnrh) anterior pituitary (fsh, lh) & posterior pituitary (oxytocin) ovaries (e, t, p4) Pineal gland produces melatonin as a response to light (less light = more melatonin; more light = less melatonin) Hypothalamus produces gonadotropin releasing hormone (gnrh) in response to melatonin. Anterior pituitary produces follicle stimulating hormone (fsh) and luteinizing hormone (lh) in response to gnrh. Posterior pituitary produces oxytocin in response to gnrh. Fsh and lh will travel to the ovaries, causing the production of estrogen (e), testosterone (t) and progesterone (p4) Uterus produces prostaglandin (pgf) and equine chorionic gonadotropin (ecg) Inhibin and estrogen will feedback to the brain communicating hormone surplus/deficiency. If the mare is pregnant, progesterone will feedback to the hypothalamus. Produced in the hypothalamus, following the release of melatonin from the pineal gland. Transported to the anterior pituitary to trigger release of fsh, lh and oxytocin.

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