BIOL 1090 Lecture Notes - Lecture 6: Cytoskeleton, Endosome, Copi

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Andrew Bendall

Document Summary

Dictyosomes: hundreds of golgi bodies (golgi complex; -apparatus) Smooth, latened, disk-like cisternae (~0. 5-1 micron in diameter: ~ 8(or fewer) cisternae/stack(few to several 1000 stacks/cell) Shows polarity: cis-medial-trans cisternae, cisternae are biochemically unique. Scafold linked to motor proteins that direct mvmt of vesicles into and out of the golgi. Diferent cisternae of the golgi contain diferent enzymes that modify proteins. The diferenial staining of the golgi cisternae relects their biochemical diferences (trans vs cis) N-linked oligosaccharides: synthesis begins in er. Protein with n-linked ogliosaccharadies arrive from er. O-linked ogliosaccharides: synthesis/ modiicaion enirely in golgi. Modiicaions of proteins in golgi can also contribute to protein targeing. Steps in the glycosylaion of a typical n- linked oligosaccharide in golgi complex . As ogliosaccharide moves through cis trans stacks, it gets modiied though the acion of integral membrane proteins whose acive sites face the lumen of the. Modiicaion of proteins and lipids: glycosylaion(glycoproteins and glycolipids, proteolyic modiicaion.