BIOL 1090 Lecture Notes - Lecture 2: Glycolipid, Cholesterol, Lipid Bilayer

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A membrane bound compartment with a characterisic content and a speciic funcion. What is a compartment: a separate secion or part of something, an area in which something can be considered in isolaion from other things. What does it achieve: compartmentalizes: divides a whole into separate parts or secions, sequesters: keeps contents from mixing with others. How is it formed: the boundary, the contents. Amphipathic: having both hydrophobic(non-polar) & hydrophilic(polar) regions. Fluidity: important feature of biological membranes: determined by: =liquid crystal: cooling decreases luidity, =crystalline gel, balance between ordered(rigid) structure and disordered structure allows: Cholesterol: regulates membrane luidity, alters packing and lexibility of lipids, if added to a liquid crystal membrane, luidity will increase, if added to a crystalline gel membrane, luidity will decrease. Lecture 2: fluid: individual lipid molecules move, mosaic: diverse paricles penetrate the lipid layer, bilayer of amphipathic lipids. Amphipathic: both hydrophobic(non-polar) & hydrophilic(polar) regions: proteins: integral(transmembrane), peripheral, and lipid-anchored, components can be mobile or interact.

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